Prior to the implementation of new devices in the clinical environment, due consideration must be given to several factors including device validity, reliability, performance, durability, practicality, portability, ease of use, sample processing time and cost. There has been a significant increase in the production and manufacture of POCT diagnostic devices over the last decade. ![]() By facilitating rapid clinical decision making and earlier targeted management of patients in the emergency department (ED), POCT has been shown to improve patient flow, reduce length of ED stay, decrease overall staff workload, improve patient satisfaction and reduce costs. Technological advances in point-of-care testing (POCT) have revolutionized the practice of emergency medicine over recent years. The Stat Profile Prime Plus ® exhibited good precision both within-run and day-to-day. The mean bias was minimal for all analytes.Ĭonclusion: There was a good correlation between the Nova Stat Profile Prime Plus ® and the Radiometer ABL800 FLEX ®/Abbott i-STAT Chem8+ ® POCT analyzers. The correlation coefficient (r) was 0.351 and ranged from 0.897 to 0.998 for all analytes. The day-to-day %CV was below 1.6% for pH, COHb, HHb, tHb, tBil, Na, K, Cl, iCa, urea, glucose and lactate, and below 6.10% for all other analytes. Results: The with-in run percentage coefficient of variation (%CV) was below 2.4% for pH, carboxyhemoglobin (COHb), deoxyhemoglobin (HHb), total hemoglobin (tHb), total bilirubin (tBil), sodium (Na), potassium (K), chloride (Cl), ionized calcium (iCa), urea, glucose and lactate, and was below 5.1% for all other analytes. Accuracy was measured by pairing individual results from the Nova Stat Profile Prime Plus ® with either the Radiometer ABL800 FLEX ® or the Abbot i-stat Chem8+ ® analyzers by calculating the differences. Paired test measurements were conducted for method comparison. ![]() Methods: A convenience sample of 150 discarded whole blood specimens was obtained and analyzed. ![]() The aim of the study was to compare the accuracy, precision and linearity of the Nova Stat Profile Prime Plus ® (Nova Biomedical, Waltham, MA, USA) to the Radiometer ABL800 FLEX ® (Radiometer South Africa Pty Ltd, Gauteng) and the Abbott i-stat Chem8+ ® (Abbott, Princeton, NJ, USA) POCT analyzers. Due to its rapid turnaround time, POCT has been shown to improve ED workflow, reduce unnecessary admissions and lessen the burden on ED staff. Background: Point-of-care testing (POCT) plays an integral role in the management of acutely ill patients presenting to the emergency department (ED).
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